Witherspoon, 45, will read Extraordinary by Penny Harrison on an upcoming episode and will become the first winner of a Best Actress Oscar to appear on the show. She won an Academy Award in 2006 playing June Cash in Walk The Line.
According to the BBC the book —illustrated by Katie Wilson — shows 'how you can discover beautiful and wonderful things, wherever you look – if you just look closely enough'.
Opening the story the Big Little Lies star says: “Sometimes, when we’re busy, it can be hard to find time to notice the world around us. The things we see every day can seem a bit… ordinary. But if you stop, and look closer, you’ll see that our world is extraordinary!"
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Witherspoon’s CBeebies Bedtime Story will air at 6.50pm, Friday, 28 January.
Reese follows a raft of other famous faces to read a Bedtime Story including Ryan Reynolds, Tom Hardy, actor Chris Evans, Tom Hiddlestone, Regé-Jean Page, Felicity Jones, David Schwimmer, Alesha Dixon, Eddie Redmayne, Orlando Bloom, Sir Elton John and Dolly Parton.
On Christmas Day, Hardy narrated The Christmas Pine by Julia Donaldson, accompanied by his dog Blue.
Hardy has proved popular on the children’s show, having previously spent a week during the first lockdown reading a new story each day.
CBeebies Bedtime Stories is on each weekday at 6.50pm on the CBeebies channel and is also available on BBC iPlayer.
Watch Ed Sheeran's Bedtime Stories