Symptom in your 20s and 30s may be an early sign of dementia

Woman suffering from wrist pain
-Credit: (Image: Getty)


A recent study has revealed that experiencing joint symptoms in your 20s and 30s might be an early warning sign of cognitive decline and dementia later in life. The research highlights a connection between inflammation during these early years and subsequent mental deterioration.

The study, which was referenced by the American Academy of Neurology, focused on the presence of C-reactive protein (CRP) in the bloodstream, an indicator of inflammation. Common signs of inflammation include joint pain, stiffness, digestive issues, and tiredness.

Dr Kristine Yaffe from the University of California commented on the findings: "Our study found that having consistently higher or moderate inflammation starting in early adulthood may negatively affect a person's ability to plan, focus and manage multiple tasks as well as how quickly they can process information in middle age."

The long-term study tracked nearly 2,400 individuals over 18 years, periodically assessing their levels of inflammation alongside their cognitive abilities.

Results indicated that participants with moderate to high inflammation were up to 21% less proficient in cognitive tests and approximately twice as likely to exhibit reduced processing speed, reports Gloucestershire Live.

Dr Yaffe highlighted: "Inflammation is important for cognitive ageing and may begin much earlier than previously known. Although current prevention efforts mainly focus on late life, our study provides evidence for the need to also target brain health in middle age. More research is needed to improve early detection of those at highest risk of poor cognitive performance and to determine effective strategies to delay the process of cognitive ageing by addressing the drivers of inflammation."

It has also been noted in other research that diets high in sugars, cholesterol, and saturated fats are associated with inflammation.