The two male victims were gunned down at a venue called “Tha Plug” in Columbus, Ohio, in the early Horus of Saturday morning.
Police in the city say that officers responded to the club at 5.10am after reports of a shooting, according to WCMH.
One man was pronounced dead at the scene while five other people were taken to hospitals in the city.
Another man was also pronounced dead after being rushed to Nationwide Children’s Hospital in a private vehicle, police said.
No information on the identities of the victims has yet been released.
The other four victims were in stable condition, with two being treated at OSU Wexner Medical Center, and two others at Grant Medical Center.
Police say that they do not yet have a suspect in custody and the investigation is ongoing.