Healy, 41, told The Sun: "I would love to do something with the girls again. I’m ready for it, any time.
“It would be best if it was all five. But if everybody isn’t on the same page and there is one that doesn’t want to do it or isn’t feeling it, they shouldn’t be forced into it.
“It is possible to do it without one member... If there was one that didn’t want to, we wouldn’t force them into it and it’s their decision, but it would be so lovely if it was all five of us.”
Humes - who now hosts This Morning and runs her own family skincare brand My Little Coco - said earlier this year she could not imagine being part of a Saturdays reunion.
She said: "I just can’t imagine doing it... It just feels like a lovely chapter that ended for me.
“I’ve got three kids and there’s so many things I turn down because they just wouldn’t work for my life. And that falls into that category.
“My life’s changed, I have a business – there’s no way I could be on tour."
Bridge, who is a member of the Loose Women panel, has spoken publicly about her battle with anxiety and depression, and previously confessed she suffered panic attacks while performing with The Saturdays.
She revealed she suffered a panic attack backstage at her first live TV appearance after being discharged from a psychiatric hospital, on BBC’s Children In Need.
She recalled: “I had a panic attack in the toilets because I was so overwhelmed. I felt I looked really sad."
King, 35, is expecting her first child after announcing her pregnancy in June. She is engaged to cricketer Stuart Broad.
Healy has just released a new solo single This Is Your Life, which has been 25 years in the making. Now she is raring to go with more fresh tracks.
The singer split from rugby player husband Ben Foden in 2018 after six years of marriage.
They have two children together, daughter Aoife, 10, and son Tadhg, seven.
Foden married new wife Jackie Belanoff-Smith after just two weeks of dating and on the day his divorce came through.
Watch: Una Healy recalls meeting Rochelle Humes and Mollie King for the first time