Brighton were defeated 3-1 by Chelsea in their campaign opener before cruising past Newcastle 3-0 despite having a man red-carded.
Meanwhile, United started their season late, stepping out last weekend for their first Premier League match of the term and putting in a weak performance en route to a 3-1 loss against Crystal Palace.
And while United responded this week in the Carabao Cup by seeing off Luton Town 3-0, they looked off the pace again until a late flourish. Brighton, meanwhile, beat Preston 2-0 in the cup competition.
Here’s everything you need to know about today’s game:
When is it?
The match will kick-off at 12.30pm BST at the Amex Stadium in Brighton.
How can I watch it?
BT Sport subscribers can watch the game live on BT Sport 1 with coverage beginning at 11.30am.
Subscribers can also view the game on channels BT Sport Extra and BT Sport Ultimate, or stream it live on the BT Sport app and website.
What is the team news?
Axel Tuanzebe is close to a return to first-team training at United, and fellow centre-back Phil Jones is the only other player missing for the visitors.
Brighton will be without long-term absentees Jose Izquierdo, Florin Andone and Christian Walton, but otherwise have no injury concerns.
Brighton: Ryan, White, Dunk, Webster, Lamptey, Bissouma, Alzate, March, Trossard, Connolly, Maupay
United: De Gea, Wan-Bissaka, Lindelof, Maguire, Shaw, McTominay, Pogba, Greenwood, Fernandes, Rashford, Martial
United have looked poor in their first two showings this term, but Marcus Rashford and Mason Greenwood getting on the scoresheet against Luton will have done their confidence some good – not that they’re usually lacking in that department. Brighton will be very much up for this fixture, however, having beaten Newcastle 3-0 last week even after losing a man. Brighton 1-2 United.