Davina McCall has revealed her misgivings about cancel culture, claiming it has created a "lack of forgiveness" in society.
The 54-year-old said social media can "lift you up" but has the power to "annihilate you as well".
"[Our job is] difficult in a different way," McCall told her former colleague Clark. "Everybody has an opinion.
"With cancel culture, and this is the new thing that I think celebrities or actors or anybody in the public eye is the most terrified of is this culture of, you say something and you get cancelled."
The TV presenter added: "I think that's such an interesting thing. I go deep when I think about things and I was thinking, 'Why is cancelling such a tough thing?'"
McCall then answered her own question as she added: "I think it's about the lack of forgiveness that anybody is allowed to have for making a mistake.
"If somebody says something and I think, that's a celebrity that I have known for many years, one of the things that I think is really weird is hauling somebody over the coals for a tweet they made in 2011."
Reflecting on her own experience within the industry, McCall said: "In 12 years, I've changed so much.
"When a journalist says to me they interviewed me eight years ago and I said this, I say, 'I've changed my mind.'
"You've got to be allowed to change your mind. Sometimes people could have been racist or homophobic 10 years ago, 12 years ago and they might have met somebody along the way who's made them change the light.
"And they could feel so ashamed of the way that they used to feel. They get hauled over the coals and they apologise and that apology is still not enough."
Clark agreed with her comments and claimed that it was the effect of the 'block button' becoming something that happens in real life – not just on social media.
When he asked McCall, "Where does it stop?", she replied: "The only way I have learned in life is by forming opinions about how I feel about things. If I listened to somebody I absolutely 100% disagree with, I can formulate an opinion about that...
"That's why programmes like Question Time are interesting because you've got all sides of the political spectrum. Sometimes there's somebody on there that drives you mad, but that's a good thing."
She added: "We must not stop the voices that annoy us or aggravate us or say something different by shaming them.
"It seems that forgiveness isn't on the agenda anymore... It seems like this loss of anybody following any kind of religion means you are unable to pardon anybody. You just will hold that vendetta against them forever, even if they are hand on heart genuinely really sorry. It seems really sad."
Last March, McCall was criticised for a tweet posted in the wake of the disappearance of Sarah Everard, in which she claimed that female abduction and murder "is extremely rare".
Watch: Davina McCall says 'beating drug addiction made me much stronger'