The budget airline has slashed at least 52 flights into and from Gatwick on Monday as air travel chaos continues across Europe.
Three EasyJet flights scheduled to and from Milan Malpensa on Monday were cancelled, along with flights in and out of Copenhagen, Bordeaux, Pisa, Faro, Budapest and Krakow.
EasyJet’s sole Monday flight to Olbia, in Sardinia, Italy was cut, along with its only Monday flight to Pristina in Kosovo, Bulgaria’s capital Sofia and Palermo in Sicily.
Flights to traditional holiday spots Amsterdam, Malta and Budapest were also scrapped.
Hurghada, a beach resort town in Egypt, was another flight destination to be cancelled by the airline.
EasyJet flights from other airports across Britain have also been cancelled, including in Manchester and Bristol.
Flights arriving from Edinburgh, Belfast International and Copenhagen were cancelled on Monday at Bristol Airport.
The cancelled flights will affect more than 100,000 passengers, the Independent reports.
EasyJet has been approached for comment by the Evening Standard.
The airline last released a statement on May 26 in response to mass flight delays and cancellations, citing IT system issues.
EasyJet passengers on Monday have also reportedly faced delays to departing and baggage collection.
Disgruntled customers have taken to Twitter, with one user claiming they have waited more than an hour to collect bags at Gatwick airport.
EasyJet axed 20 flights from Gatwick last week due to strike action in Italy including departures to Bologna, Milan, Naples, Rome and Venice.
Airlines are in disarray while travel demand peaks in the summer months, and off the back of an easing of Covid restrictions in many countries.