Explosions rock airbase as Israel reportedly hits back at Iran

Photos show plumes of smoke rising into the air following a reported strike around the Iranian city of Isfahan.

It's being reported that explosions were heard and airspace closed around the city, as Israel retaliated against Iran. Isfahan is home to a major airbase for Iran's military and is associated with the country's nuclear program, which was not believed to be the target of the attack.

Commercial flights over Iranian airspace have been diverted and a US official confirmed to ABC News that missiles hit a site in Iran. The semi-official Fars news agency reported on the sound of explosions over Isfahan, the country's third largest city, near its international airport.

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Retired US Army General Mike Lyons told CNN: "I think they used manned aircraft in this operation to ensure their targeting was precise. They went after military targets. This sends a signal to Iran that we can strike that facility (Isfahan's nuclear plant) if we want."

Iranian Press TV is also reporting an explosion was heard near the central city. All flights heading to "Tehran, Isfahan and Shiraz, the airports of the West, North West and South West have been suspended," the director of Iran's public relations for an airport company announced in an interview with state-run Mehr TV.

Just hours before the explosions were heard, Iranian Foreign Minister Hossein Amir-Abdollahian told CNN that Iran's response if Israel took any further military action against it would be "immediate and at a maximum level". He said: "In case the Israeli regime embarks on adventurism again and takes action against the interests of Iran, the next response from us will be immediate and at a maximum level."

This comes after Iran launched hundreds of missiles and drones at Israel at the weekend after two Iranian generals were killed when an Iranian consular building in the Syrian capital of Damascus was hit by a suspected Israeli strike. Iran's weekend strike was mostly intercepted and caused little damage.

Israeli Prime Minister Benjamin Netanyahu said: "Israel will do whatever is required to defend itself". Israeli leaders had vowed to respond to Iran's attack, with Prime Minister Benjamin Netanyahu making plans with his top officials over the last few days. On Monday, Israeli military chief Lt. Gen. Herzi Halevi said Israel is considering its next steps but the Iranian strike "will be met with a response."

While he gave no further details on the specifics, the army's spokesman, Rear Adm. Daniel Hagari, claimed Israel will respond "at the time that we choose." The US has urged Israel to show restraint, despite an Israeli official stating: "Any response will be coordinated with the Americans."

US President Joe Biden previously told Netanyahu that his country would not participate in any counteroffensive against Iran. US State Department spokesperson Matthew Miller said Israel and other nations were "effective" at neutralizing the threat from Iran over the weekend, adding that the attack could have caused a "significant loss of life."

He said Biden and Secretary of State Antony Blinken have "consulted extensively with partners in the region and around the world." They are calling for the international community to "act as a united front".

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