The pair were both contestants on the 2006 series of the reality show.
Speaking on This Morning, he said: “Do you know what, we did a Requiem service for Nikki, and I know she’s passed away but every time I think of her I smile, I laugh.
“She was such a great energy.”
Wise also shared that he reached out to Grahame’s mum after her death.
“I sent a message to her mother just because I know her mother is a woman of faith as well, so that kind of helped her through,” he said.
"But I know Nikki will be looking down on us and smiling and laughing now."
Watch: Glyn talks on This Morning about his faith
Wise, who was just 18 when he went on the reality show, is currently training to become a priest.
"I grew up in a religious family, got baptised and went to Sunday school as a kid," he said.
“I prayed my way into Big Brother.
"I was asking God, 'Can you please just get me into the Big Brother house?' I also went on holiday to Ireland and I kissed the Blarney Stone as well, and asked, ‘Can I go into Big Brother please?'"
Wise said getting onto the reality show was a dream of his because he wanted something to “completely change my life”.
“And it did, Big Brother did that,” he added.
Watch: Pete Bennett said he thought 'love and support' would help change Nikki Grahame