Mercurio, who serves as executive producer on the forthcoming ITV series about bomb disposal operatives, wrote BBC smash hit Line Of Duty, and both dramas feature McClure in a leading role.
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Inevitably, Trigger Point is drawing comparisons to their most famous show, but both said that they were happy to cash in on some of the police procedural's success.
McClure told Yahoo and other press: "I'm not concerned, this is what actors do. I've fallen into this genre and Line Of Duty, we never expected it to do what it's done and I can't be worried about taking roles that might feel in a similar world because of that.
"I don't see (the two characters) together as the same people at all. They're both very strong women for sure and very brave and very committed, but that's the kind of roles I love to take, if I read a script I often want to play the male's role because that is the strong, committed role, so I'm always going to be drawn to that.
"People loved Line Of Duty so if there are any comparisons, it might not be a bad thing."
Mercurio agreed: "We're very proud of our collaboration on Line Of Duty and obviously thrilled at the way that series has connected with such a large audience, but I think the audience will realise this is a very different piece of work.
"It's great if people come to it because they love Vicky from Line Of Duty and they want to see her in this, so that would be lovely if it gives the show more attention."
Line Of Duty is known for its traditional approach of airing in weekly episodes rather than being made available all at once top stream and Mercurio spoke about how important he felt it was to still make "appointment to view" TV.
He said: "It's about serving the audience, there's still a big section of the audience who love the experience of appointment to view TV.
"If something becomes a talking point and people have lots of theories about what's going to happen next and who's behind some particular mystery, elements that we do have in Trigger Point, I think it all adds to the shared experience of television viewing.
"Obviously the trend is away from that...But every now and then we see how refreshing people find it when they are able to join in the experience of talking about TV that other people have seen. It's almost like we're turning the clock back to an earlier age of television and there are still plenty of people who really appreciate that."
Trigger Point will air on ITV in 2022.
Watch: Vicky McClure and Martin Compston to get AC-12 tattoos after Line Of Duty finale