The heir to the throne expressed his desire to do more to help flood-affected residents and asked his aides to speak to insurance companies and other authorities to provide financial assistance.
"Let’s see if there is a way of finding a bit of help,” Charles said during a visit to Kookoo Madame, a boutique and gift shop, run by shopowner Emma Jamal.
Ms Jamal says she has lost stock worth “hundreds of thousands of pounds” after 4 feet of water destroyed everything.
Charles, 71, has said he is concerned at insurance firms' refusal to pay out for flooded businesses.
More than 1,000 homes and businesses in Rhondda Cynon Taf have been affected by heavy rain.
Around 200 people gathered to meet Charles in the town centre, parts of which were left underwater after the river reached its highest level in 40 years.
He spent an hour meeting people including first responders and shown his support of those who have been at the frontline dealing with the severe flooding in the wake of the storm.
Seven road and pedestrian bridges have been condemned and the bill for wider damage in the area will run into millions.
Thousands of jobs are at risk because of the damage - an industrial estate employing 4,000 in Treforest alone is devastated - and there are fears for the safety of coal tips after a number of landslips.
In the town, Charles visited The Prince’s Cafe, which has been put out of business for now after 7ft of water came into the basement on Sunday and wrecked the baking area.
A Met Office yellow weather warning for rain has been issued this weekend over some areas of England and Wales while communities continue to repair the damage caused by the floods.
The heavy rain forecast could mean more flooding for some of the most vulnerable areas in the process of major clear-up operations.
And the Environment Agency has warned that downpours could continue into next week and a spokesman said "ongoing river flooding remains probable for the River Severn on Monday and Tuesday".
More than a month's rain fell in 48 hours on Saturday and Sunday.
Prince Charles' visit follows his first engagement in the country which first saw him visit the CAF train factory in Newport where he will meet employees and learn about the production process and officially open the facility.
We then saw him test drive Aston Martin’s new luxury SUV at the car maker’s factory in St Athan, near Barry.
He also visited the Marie Curie Hospice in Penarth, of which he is a Patron, to meet with patients and staff before he went on to meet those affected by flooding.