Zinedine Zidane, who has overseen three of those triumphs from the dugout, will aim to return Real to their perch following two seasons well out of the reckoning.
Real were beaten across both legs by Manchester City in the round of 16 last season, but have a favourable Group B draw this time around as they face Inter Milan, Shakhtar Donetsk and Borussia Monchengladbach in Group B.
The Final is set to be held at Istanbul's Ataturk Olympic Stadium, which was originally picked to host the 2019-20 showpiece before coronavirus altered the conclusion of the competition. Saint Petersburg, the original city selected to stage this season's Final, will now stage the 2021-22 event.
Who Real Madrid will face in the group stages