Miocic finally gets his wish of a rematch against pound-for-pound great Cormier, who took the heavyweight championship from the American after delivering a devastating first round knockout in their first meeting 13 months ago.
Diaz meanwhile fights for the first time since his August 2016 defeat to Conor McGregor, taking on former lightweight champion Anthony Pettis.
Yoel Romero is also in action against undefeated Paulo Costa.
Date, UK start time and venue
It is an early start for UK viewers - the main card for UFC 241 gets underway in the early hours of Sunday morning at 3am BST.
Ringwalks for Cormier vs Miocic are not expected until 5am.
The prelim show gets underway at 1am.
TV channel and live stream
UFC 241 will be televised live on BT Sport 1, with their pre-fight show getting underway at midnight.
Betting odds | Provided by Betfair | Subject to change (UK and Ireland only)
- Cormier to win by KO/TKO: 9/4
- Cormier to win via points: 9/2
- Miocic to win by KO/TKO: 15/8
- Miocic to win via points: 7/1
Cormier to win via first round TKO.
- Daniel Cormier vs Stipe Miocic - heavyweight title fight
- Anthony Pettis vs Nate Diaz - welterweight bout
- Yoel Romero vs Paulo Costa - middleweight bout
- Gabriel Benitez vs Sodiq Yusuff - men’s featherweight bout
- Derek Brunson vs Iain Heinisich - middleweight bout
- Clay Collard vs Devonte Smith - lightweight bout
- Raphael Assuncao vs Corey Sandhagen - men’s bantamweight bout
- Manny Bermudez vs Casey Kenney - men’s bantamweight bout