Qatar are out of the World Cup - the first time a host nation has been eliminated after two games.
The Netherlands' 1-1 draw with Ecuador on Friday was enough to seal the Middle Eastern country's fate after the home side lost 3-1 to Senegal earlier in the day.
Last Sunday, Qatar were defeated 2-0 by Ecuador in the tournament opener. They are on 0 points and a goal difference of -4.
Qatar still have to play their third group match on Tuesday, against the Netherlands.
But even if the hosts won that clash, they would still only be on 3 points and would not be able to finish Group A in the top two.
Only the winner and runner-up in each group go through to the last 16 stage of the competition.
The Netherlands and Ecuador are both on 4 points.
Senegal, the African champions, lie in third spot with 3 points and theoretically could still progress if they overcome Ecuador on Tuesday.
At the Khalifa Stadium, the Dutch went in front thanks to a stunning strike from PSV Eindhoven forward Cody Gakpo on 6 minutes.
Ecuador then levelled matters in the 49th minute courtesy of Enner Valencia who tapped in his third goal of the tournament.
The South Americans had a goal from Brighton wing-back Pervis Estupinan disallowed on the stroke of half-time and also hit the bar close to the hour mark through Gonzalo Plata.