Hospitals in Greater Manchester are running low on beds to treat coronavirus patients, with at least two sites operating at full capacity, figures seen by Sky News suggest.
Data from the Greater Manchester Critical Care Network (GMCCN) suggested some of the region's 12 hospitals were running out of space on Friday.
The figures showed the Stepping Hill Hospital and the Salford Royal NHS Foundation Trust were operating at full capacity.
It also showed the Royal Bolton Hospital was running at 94% capacity
The figures show hospitals across Greater Manchester are operating at an average of 82% capacity.
The data emerged as the Greater Manchester mayor Andy Burnham continued to clash with Boris Johnson over Tier 3 status and cash to support businesses forced to close.
The NHS said in a statement: "We are monitoring the situation with our hospital admissions, overall beds and ITU beds very very closely.
"It's not unusual for 80% to 85% of ICU beds to be in use at this time of year and our hospitals work together if there are particular pressures in any one area, to ensure the best care for patients who need the high level of support ICU provides, both for Covid and for other reasons."
A source at the GMCCN told Sky News the NHS usually say they're "at capacity" when they hit 85%, not 100% of beds filled.
A spokesperson for the NHS in the North West has said: "Coronavirus cases are rising and it is obviously a serious situation so it is vital everyone does what they can to control the virus."
It is also being reported that after Mr Burnham held "constructive" talks with Mr Johnson's senior aide Sir Edward Lister, the prime minister is now ready to offer tens of millions of pounds to head off a Tier 3 revolt.
Mr Burnham has written to Mr Johnson and other party leaders proposing a Commons debate and vote to "break the impasse" and establish a cross-party consensus on financial aid for Tier 3 areas.
Communities Secretary Robert Jenrick claimed "the contours of an agreement are there".
But he warned a deal needed to be struck on Monday or Tuesday or the government would have to impose measures "to protect the NHS and bear down on the virus".
And he hinted parts of South and West Yorkshire could also be placed into the highest band of restrictions in England, telling Sky News' Kay Burley "we'll be discussing the same issues" with local politicians there.
In total, the UK recorded another 16,171 positive cases on Sunday and a further 150 COVID-related deaths.
That brings the total number of deaths to 43,579.
But separate figures from the UK's statistic agencies suggest up to 58,500 people have died with the virus mentioned on their death certificate.
The reported beds crisis in Manchester came after Mr Burnham disputed a claim by the prime minister in a Downing Street news conference on Friday, when he said the coronavirus outbreak in Manchester was "grave" and cases had doubled in the last nine days.
Mr Burnham said in a Sunday TV interview: "I think it was an exaggeration of the position that we're in. Of course it's a matter of concern, and we watch the figures very closely indeed.
"But the figures have been falling in Manchester itself in the last few days, across Greater Manchester up slightly but certainly not doubling every nine days."
Although Mr Burnham's criticism of Mr Johnson prompted Cabinet Office minister Michael Gove to accuse the mayor of "posturing", it is reported the prime minister is ready to offer extra cash for the region if a deal on Tier 3 is reached.
The Times reports that Downing Street has not ruled out imposing Tier 3 status on Greater Manchester, but has accepted it is more likely to work if backed by local leaders.
Significantly, Mr Burnham's demands for more cash are being backed by Sir Graham Brady, MP for Altrincham and Sale West and chairman of the Conservative backbench 1922 Committee.
But cracks began to appear in Tory backing for Mr Burnham when five Conservative MPs from Greater Manchester wrote to him urging him to do a deal "around the negotiating table and not via loud-hailer".
Earlier, proposing a Commons debate and vote, Mr Burnham urged party leaders: "We recognise the uncertainty that this is causing and write to ask for your help in breaking the impasse and finding a fair resolution.
"This could be done by parliament calling an urgent debate and vote this week to establish a cross-party consensus on what constitutes a fair financial framework for people in areas under Tier 3 restrictions."
And on Monday he tried to play down pressure from the government, telling Sky News "nothing's changed as far as I'm concerned".
"It's not about the size of the cheque, it's about protecting low-paid workers, people who are self-employed and businesses from collapsing," he said.
"We've always said we'll put people's health first and we will do that, but health is about more than controlling the virus."
Elsewhere, Wales is expected to announce a "fire break" lockdown to curb the rate of infection. If it gets the green light it will begin on Friday and last for 17 days, a leaked document claimed last week.
In Ireland, the cabinet is meeting to make a final decision on whether to impose its highest Level 5 measures - equivalent to England's Tier 3 - as part of a six-week lockdown, after its National Public Health Emergency Team recommended harsher restrictions.
It is understood that a middle ground between Level 4 and Level 5 is a probable scenario for the coming weeks.
Watch and follow 'Postcode Lockdown: A Divided Nation' on Sky News from 9pm on Monday, as it examines which strategy is best for Britain