Around 300 fans had convened outside what was once the East Stand at their former ground Highbury an hour before kick-off, they were then set to march to the Emirates ahead of a game in which Arsenal, trailing 5-1 from the first leg, have little chance of qualification.
Wenger has been offered a two-year deal but is yet to decide whether to extend his over two decade spell at Arsenal.
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Fan discontent has been growing in recent weeks, the humbling at the German champions in the first leg having been followed by convincing losses at Chelsea and Liverpool that have seen Arsenal slip out of the top four of the Premier League.
"Wenger Out" chants louder than "Arsenal, Arsenal, Arsenal" pic.twitter.com/MZR0Mhqn3I— James Benge (@jamesbenge) March 7, 2017
“I’ve had enough. I’ve been a supporter of this club since I was 11 years old,” Mark Hoffman, 58, from Archway told Standard Sport.
“I’ve stood on the North Bank for years. The manager’s been great for the first 10 years and awful for the second 10.
"It’s not just the manager, it’s the board, the ownership. They have no ambition to win anything.
“Is my voice being heard by the club? Absolutely not. The club hasn’t listened to the voice of fans since it left this ground.”
It is expected that thousands of seats at the Emirates will be empty at kick-off, with Arsenal’s ticket exchange receiving an unheralded number of returns for a fixture of this magnitude.