Slaven Bilic had hoped that Lanzini would recover from a leg injury in time to be involved but the playmaker is not now expected to return to full training until next week.
Bilic will, however, be boosted by the return of Michail Antonio to his squad. The England international missed last weekend’s 4-0 defeat at Manchester United as he recovers from a hamstring injury but has since played for the Under-23 team.
Andy Carroll is also back in full training, as is midfielder Cheikhou Kouyate, who has a chance of making the substitutes’ bench.
Meanwhile, West Ham remain hopeful of adding Portuguese holding midfielder William Carvalho to their squad before the transfer window closes but are not prepared to match Sporting Lisbon’s asking price of £40million.
Speaking on Sky Sports, West Ham vice-chairman Karren Brady said chairman David Sullivan was working “20 hours a day” on possible deals while another club source revealed today the Carvalho deal “had always been 50-50” but they were “battling on” in an effort to sign the player.