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The announcement that the 37-year-old boxer is to take part in the BBC show as part of the first same-sex couple has already sparked over 100 complaints.
But Adams told the Radio Times: “I'm expecting the same sort of thing I got with women's boxing in the beginning – there will always be some resistors, but once they know you're here to stay, they get used to it.
“Women dance together all the time in nightclubs. Traditionally I guess men and women would dance together when they were courting, so the older generation have that in their heads. They see it as a sexual thing rather than a sport.
Watch: Nicola Adams says it’s time for change on the Strictly dancefloor
“I've been through so much in my life. I've been through my mum and dad separating, domestic violence, back injuries, having to look after my brother when I was 13 when my mum had meningitis.
“So someone's going to comment on Twitter? It's nothing, it won't faze me at all. It's like – try harder. If they don't like it, they're going to have to deal with it or switch to another channel.”
The boxing champion – who retired undefeated in 2019 – has been in a relationship with 22-year-old model Ella Baig for two years.
And Adams said she would not have signed up to Strictly unless she was able to dance with a woman.
She said: “I wouldn't have done it otherwise. I wish I could say it's because I wanted to be a role model, but it didn't even cross my mind at the start. I think it's cool to let kids see someone who represents them, but for me it just felt more comfortable.”
The celebrity contestant’s professional dance partners have not been officially announced but Adams has fuelled rumours she is to be partnered with Russian pro dancer Katya Jones as they were photographed leaving filming together.
While it will be the first competing same-sex partnership on the show, last year saw two professional male dancers perform together in a routine.
The dance between Johannes Radebe and Graziano di Prima was said to have received almost 200 complaints.
The BBC subsequently issued a statement noting Strictly "is an inclusive show" and that it was "proud to have been able to facilitate" the performance between the two men.
About eight million people tuned in to watch the dance show each week.
Italy, Germany and Ireland have already featured same-sex couples in their versions of the dance show.
And earlier this year ITV’s Dancing On Ice partnered Steps singer Ian “H” Watkins with professional skater Matt Evers.
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