The warning comes two days after the UN Security Council unanimously approved new sanctions to punish the secretive nation including a ban on coal and other exports worth over £770 million.
Sanctions were imposed after the North’s latest round of intercontinental ballistic launches, which the regime claims has the ability to reach American soil.
North Korea’s statement said the sanctions were caused by a “heinous US plot to isolate and stifle” the county.
It says the UN sanctions will never force the country to negotiate over its nuclear programme or to give up its nuclear drive.
It also says the country will take “action of justice” but did not elaborate on what that might entail.
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The statement was carried by state media.
President Donald Trump and South Korean president Moon Jae-in spoke of their concern over Pyongyang’s nuclear ambitions during a phone call on Sunday.
Both leaders reaffirmed the “grave and growing” threat North Korea poses to countries around the world.