Britain's Jonnie Peacock has sealed his status as the fastest amputee runner in the world after winning the T44 100 metres in a new Paralympic record.
The 19-year-old athlete stormed away from the field and finished in a time of 10.90 seconds, ahead of American Richard Browne, who was second in 11.03secs and South Africa's Arnu Fourie, who ran 11.08secs to scoop bronze.
Defending champion, South African 'Blade Runner' Oscar Pistorius, who was runner-up in the 200m, was never in contention this time around, ending up fourth in 11.17secs.
Chants of 'Peacock, Peacock, Peacock' rang around the Olympic Stadium in east London before the start of the final, which was delayed when 200m winner Brazilian Alan Fonteles Oliveira appeared to twitch and the field were asked to stand up.
He was judged to have made a faulty rather than a false start, but the added tension did not affect Peacock, who did a lap of honour draped in the Union Flag after his win.
In a week that had been dominated by a war of words between Pistorius and Oliviera, Peacock showed just why he was such an overwhelming favourite going into the race.
Pistorius had claimed after his second place in the 200m that some competitors were being given an advantage by having longer prosthetic legs.
The row deepened when the South Africa team said others were changing their legs between races, against Games rules.
Cambridge-born runner Peacock now adds Paralympic gold to the world record of 10.85secs he set in July.
His victory crowned a golden night for ParalympicsGB, coming minutes after David Weir claimed his third gold, adding the T54 800m to his 1,500m and 5,000m titles.
The 33-year-old 'Weirwolf' is also due to take part in Sunday's marathon, which could see him land a fourth victory.
Also in the Olympic Stadium, 'Hurricane' Hannah Cockroft won her second gold of the Games.
The 20-year-old claimed she felt like she was "flying" after a dominant run in qualifying and lived up to her nickname in emphatic fashion in the final by storming to T34 200m glory.
The Halifax racer, the world record holder and already the 100m champion, finished in 31.90secs, more than two seconds clear of the field.
Swimmer-turned-cyclist Sarah Storey won her fourth gold of the Games to match Baroness Tanni Grey-Thompson's British female record of 11 Paralympic titles.
The 34-year-old reached the landmark with victory in the women's C5 64km road race time trial at Brands Hatch in Kent.
Manchester-based Storey crossed the finishing line more than seven minutes ahead of her rivals, and was so fast she caught the male race - which had set off earlier.
It followed her wins in the 16km road time trial and the 500m time trial and pursuit in the Velodrome.
Storey won five Paralympic golds in swimming before transferring to the track in 2005 because of an ear infection, and now has six in cycling. Her incredible career spans 20 years and six Games since she made her debut in Barcelona aged just 14.
At the Aquatics Centre, schoolboy swimmer Josef Craig became a Paralympic champion at the age of 15.
The Briton, who was born with cerebral palsy, broke his own world record, set earlier in the day, to storm to victory in the S7 400m freestyle.
Meanwhile, Helena Lucas triumphed in the 2.4m one-person keelboat at Weymouth.
Britain's Paralympians have now surpassed their medal target for the Games.
UK Sport set a target of claiming at least 103 medals - one more than was won in Beijing in 2008 - and that mark was hit when swimmer Heather Frederiksen won silver in the women's S8 100 metres freestyle.
"These have been incredible games for ParalympicsGB," said Baroness Sue Campbell of UK Sport. "Already we are now planning for Rio 2016 and making the big decisions to ensure this success continues."
The extra golds meant Great Britain were in second place in the medals table behind China, and just in front of Russia.