ITV's Strictly The Real Full Monty will see celebrities including Blue singer Duncan James, Christine McGuinness, and former Strictly couple James and Ola Jordan take everything off to raise awareness for cancer checks.
The group will perform their strip tease in Blackpool this Christmas, where they'll add in glitz, glamour and some ballroom elements to their routine.
Also stripping off for the 2021 show are EastEnders Big Mo actress Laila Morse, Olympic athlete Colin Jackson, musical theatre and Loose Women star Brenda Edwards, Homes Under the Hammer presenter Martin Roberts, and Love Island favourites Teddy Soares and Demi Jones.
All of the celebrities taking part have had their lives touched by cancer in some way and will speak about their reasons for taking on the brave challenge to encourage viewers to check themselves for signs of cancer.
They'll be coached in their risque routine by Diversity star Ashley Banjo, who is back once more to help out the nervous celebrities with their choreography.
He said: "I'm so excited to be working with a new brilliant, bold and brave line-up of celebrities for Strictly The Real Full Monty.
"It's going to be our biggest musical dance extravaganza yet and we are determined to get the message out there that early cancer checks in intimate areas save lives.
"So don't forget to check your bits and baubles this Christmas!"
ITV factual commissioner Kate Teckman added: "This year we’re bringing our message with a bang by adding a huge dose of sequins, sparkles, sambas and salsas to the strip.
"There’ll also be star guest performances and stunning solos so hold onto your mirror balls – this is strictly the most ambitious Full Monty yet!"
Previous years have included Alexander Armstrong, Coleen Nolan, James "Arg" Argent and Michelle Heaton stripping off for the cause.
Watch: Jim Davidson storms out of racism conversation with Ashley Banjo