The TV star was hosting the ITV morning show with Kate Garraway and they were talking to a traveller on video, a man who had been affected by the flight chaos.
“It’s a good job you kept your passport on you,” Madeley pointed out as they talked.
"And it’s a good job you’ve got a couple of credit cards on you as well.
"Otherwise you really would be stuck, you would just basically be sitting on your a***."
Garraway, 56, looked slightly surprised at her co-presenter’s choice of word as she sat quietly beside him.
But the TV star quickly realised his gaffe and put it right.
Throwing his hands up in the air he said to viewers: “Excuse me.”
He then repeated the sentence but used the word “bottom” instead.
"Sitting on your bottom, at the airport on the floor, which so many people are," he said.
Madeley, 67, and Garraway then pressed on with a chat about the man’s comfy choice of clothes for travelling.
While Madeley was quick to correct his mistake, the little slip up didn’t go unnoticed and was spotted by some viewers who then shared their reactions on Twitter.
One person posted a confused emoji as they asked: “Did Richard Madeley just say a***?”
Another fan tweeted a crying with laughter emoji as they laughed that they had only been watching for five minutes and had heard the cheeky word.
“I do believe Richard Madeley just said 'a***' live on air,” posted someone else.
Watch: Richard Madeley challenges Steve Barclay on migrant boats